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Products Details
Product Description
– Xanthine oxidase-IN-5 is an effective and orally active xanthine oxidase (XO) inhibitor with IC50 value of 0.70 μM. Xanthine oxidase-IN-5 displays favorable agent-like properties with ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 shows potent hypouricemic effects in hyperuricemic rat model[1].
Web ID
– HY-144456
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C18H16FN3O3
References
– [1]Zhang TJ, Zhang Y, Zhang ZH, et al. Discovery of 4-(phenoxymethyl)-1H-1,2,3-triazole derivatives as novel xanthine oxidase inhibitors. Bioorg Med Chem Lett. 2022;60:128582.
CAS Number
– 2276711-87-4
Molecular Weight
– 341.34
SMILES
– O=CC1=CC(F)=CC=C1OCC2=CN(CC3=CC=CC(OC)=C3)N=N2
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Xanthine Oxidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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