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Products Details
Product Description
– EZH2-IN-12 (Compound 5) is a potent inhibitor of EZH2. EZH2-IN-12 has the potential for the research of central nervous system malignancies[1].
Web ID
– HY-144330
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H23Cl2N3O3
References
– [1]Liang R, et al. A Chemical Strategy toward Novel Brain-Penetrant EZH2 Inhibitors. ACS Med Chem Lett. 2022;13(3):377-387.
Molecular Weight
– 460.35
SMILES
– CC1=CC(C)=C(C(N1C)=O)CN2CCC3=C(C=C(C(Cl)=C3C2=O)C4=C(ON=C4C)C)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Isoform
– EZH2
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
