Download Files:
Products Details
Product Description
– MPGES-1 is considered as a promising therapeutic target of the next generation anti-inflammatory drugs in the research of inflammatory diseases. The IC 50 value of mPGES-1-IN-1 is 0.03 μ M。
Web ID
– HY-144238
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H14N4O2S
References
– [1]Ergül AG, et al. Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase. Eur J Med Chem. 2022 Mar 5;231:114167.
CAS Number
– 2914158-00-0
Molecular Weight
– 386.43
SMILES
– S=C1NN=C(O1)C2=CC=C3NC(C4=CC=C(C=C4)OC5=CC=CC=C5)=NC3=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PGE synthase
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
