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Products Details
Product Description
– DHODH-IN-19 is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-19 inhibits tumor growth. DHODH-IN-19 has the potential for the research of cancer and inflammation disease (extracted from patent WO2021238881A1, compound 1)[1].
Web ID
– HY-144169
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C22H18ClF6N3O3
References
– [1]Shuhui Chen, et al. Triazolones. Patent WO2021238881A1.
CAS Number
– 2742675-85-8
Molecular Weight
– 521.84
SMILES
– O=C1N(C2=CC(O[C@@H](C)C(F)(F)F)=C(C=C2F)/C(F)=C/C3=C(C=CC=C3F)Cl)N=C(N1CC)CO
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
