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Products Details
Product Description
– RIP1 kinase inhibitor 4 (Example 3) is a BBB-penetrable RIP1 kinase inhibitor (EC50: <100 nM). RIP1 kinase inhibitor 4 can be used for the research of cell programming necrosis-related diseases[1]. RIP1 kinase inhibitor 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-153434
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H23N5
References
– [1]Su, Yaning, et al. Preparation of pyrazole and triazole heterocycle derivative as RIP1 kinase inhibitor. Patent. WO2023040870.
CAS Number
– 2919836-00-1
Molecular Weight
– 369.46
SMILES
– NC(N=C1)=NC=C1C#CC2CCC(C2)N3N=C4C(CCC4C5=CC=CC=C5)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RIP kinase
Isoform
– RIPK1
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
