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Product Description
– HER2-IN-5 is a potent and orally active HER-2 inhibitor, example 10, extracted from patent WO2021164697[1].
Web ID
– HY-143733
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H33N7O3
References
– [1]Yihan Wang, et al. Substituted amide derivative and composition thereof and use thereof . Patent WO2021164697.
CAS Number
– 2691891-36-6
Molecular Weight
– 503.60
SMILES
– O=C(C1=C2C(N)=NC=CN2C([C@H]3CN(C(C=C)=O)CCC3)=N1)NC4=CC=C(CC(N(C)C)=O)C(C)=C4C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Isoform
– ErbB2/HER2
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
