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RIPK1-IN-9
$610
Only 1000 item(s) left in stock.
Products Details
Product Description
– RIPK1-IN-9 (example 45), a dihydronaphthyridone compound, is a potent and selective RIPK1 inhibitor. RIPK1-IN-9 inhibits U937 cell (IC50=2 nM) and L929 cell (IC50=1.3 nM)[1].
Web ID
– HY-143727
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H25FN6O2
References
– [1]Fusheng Zhou, et al. Dihydronaphthyridone compounds, their preparation and pharmaceutical uses. WO2021160109A1.
CAS Number
– 2682889-57-0
Molecular Weight
– 472.51
SMILES
– O=C1C2=C(N=CC(C3=CC4=NC(N)=NN4C=C3)=C2)CCN1CC5=CC(F)=CC=C5OC6CCCC6
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– RIP kinase
Isoform
– RIPK1
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
