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Products Details
Product Description
– sEH inhibitor-2 (compound 5l) is an orally active (predicted percentage absorption: 71.2-88.4%) soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 0.9 nM. sEH inhibitor-2 can maintain epoxyeicosatrienoic acids (EETs) serum level in high concentrations. sEH inhibitor-2 can be used in study of cardiovascular protection[1].
Web ID
– HY-143294
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H18N4O3
References
– [1]Rezaee, E, et al. Design, synthesis, and biological evaluation of some 1,2,3-triazole derivatives as novel amide-based inhibitors of soluble epoxide hydrolase. Med Chem Res 30, 1738–1746 (2021).
CAS Number
– 2816102-69-7
Molecular Weight
– 398.41
SMILES
– O=C(C1=CC=CC=C1C(NC2=CC=C(C=C2)CN3C=C(N=N3)C4=CC=CC=C4)=O)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Epoxide Hydrolase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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