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Products Details
Product Description
– OI338 is an orally available, ultralong-acting insulin analogue.
Web ID
– HY-142663
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C260H403N65O84S6
References
– [1]Kjeldsen TB, et al. Engineering of Orally Available, Ultralong-Acting Insulin Analogues: Discovery of OI338 and OI320. J Med Chem. 2021 Jan 14;64(1):616-628.
Molecular Weight
– 5971.76
SMILES
– O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CSSC[C@@H](C(NCC(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H]([C@H](O)C)C(N5[C@@H](CCC5)C(N[C@H](C(O)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCCCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC6=O)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)NC7=O)C(N[C@@H](CSSC[C@@H](C(NCC(N[C@@H](CO)C(N[C@@H](CC8=CNC=N8)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC9=CC=C(C=C9)O)C(N[C@@H](CC(C)C)C(N[C@H]6C(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC(C)C)NC([C@H](CC%10=CNC=N%10)NC([C@H](CCC(N)=O)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](CC(O)=O)N)=O)=O)=O)=O)=O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@H]7[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)CN
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Insulin Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
