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Products Details
Product Description
– CP 316311 is a potent and selective CRF1 receptor antagonist with an IC50 value of 6.8 nM.
Web ID
– HY-14129
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C21H29NO2
References
– [1]Chen YL, et al. Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists. J Med Chem. 2008 Mar 13;51(5):1377-84.
CAS Number
– 175139-41-0
Molecular Weight
– 327.46
SMILES
– CCC(CC)OC1=C(C)C(OC2=C(C)C=C(C)C=C2C)=NC(C)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– CRFR
Isoform
– CRFR1
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
