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Products Details
Product Description
– BTK inhibitor 19 is a highly selective, covalent BTK inhibitor (IC50 = 2.7 nM).
Web ID
– HY-139881
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H24F3N7O3
References
– [1]Ma C, et al. Discovery of 1-Amino-1H-imidazole-5-carboxamide Derivatives as Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitors. J Med Chem. 2021 Nov 11;64(21):16242-16270.
CAS Number
– 2557174-19-1
Molecular Weight
– 527.50
SMILES
– NC(C1=C(C2=CC=C(C(NC3=NC=CC(C(F)(F)F)=C3)=O)C=C2)N=C([C@@H]4CCCCN4C(C=C)=O)N1N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Btk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
