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Products Details
Product Description
– MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.
Web ID
– HY-139832
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H19N5O4S3
References
– [1]Martínez-González S, et al. Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors. ACS Med Chem Lett. 2021 Nov 2;12(11):1794-1801.
CAS Number
– 1414453-58-9
Molecular Weight
– 549.64
SMILES
– CC1=C(C2=CN=C(OC)C(NS3(=O)=O)=C2)SC4=C1N=CN=C4C5=CC=C(CNC(C6=CC3=CC=C6)=O)S5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– mTOR;PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
