Download Files:
Products Details
Product Description
– Dolastatinol is a synthetic analog of dolastatin 10 and low nanomolar inhibitor of tubulin polymerization.
Web ID
– HY-139625
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C43H70N6O7S
References
– [1]Gutman H, et al. Discovery of Dolastatinol: A Synthetic Analog of Dolastatin 10 and Low Nanomolar Inhibitor of Tubulin Polymerization. ACS Med Chem Lett. 2021 Sep 7;12(10):1596-1604.
CAS Number
– 2759918-83-5
Molecular Weight
– 815.12
SMILES
– OCC1=CSC([C@H](CC2=CC=CC=C2)NC([C@@H](C)[C@@H]([C@]3([H])N(CCC3)C(C[C@H](OC)[C@H]([C@H](C)CC)N(C)C([C@@H](C(C)C)NC([C@H](N(C)C)C(C)C)=O)=O)=O)OC)=O)=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Microtubule/Tubulin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
