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M1002
$130 – $143
Products Details
Product Description
– M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist, and can enhance the expression of HIF-2 target genes. M1002 shows synergy with prolyl-hydroxylase domain (PHD) inhibitors[1].
Web ID
– HY-139287
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C15H8F6N2O2S
References
– [1]Dalei Wu, et al. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019 Apr;15(4):367-376.
CAS Number
– 823830-85-9
Molecular Weight
– 394.29
Compound Purity
– 99.11
SMILES
– O=S1(N=C(C2=C1C=CC=C2)NC3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMF : 50 mg/mL (ultrasonic)|DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
