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UNC 0631
$138 – $815
Products Details
Product Description
– UNC 0631 is a potent histone methyltransferase G9a inhibitor with an IC50 of 4 nM. UNC 0631 potently reduces H3K9me2 levels in MDA-MB-231 cells with an IC50 of 25 nM[1].
Web ID
– HY-13808
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C37H61N7O2
References
– [1]Liu F, et al. Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines. J Med Chem. 2011 Sep 8;54(17):6139-50.
CAS Number
– 1320288-19-4
Molecular Weight
– 635.93
Compound Purity
– 98.35
SMILES
– COC1=CC2=C(NC3CCN(CC4CCCCC4)CC3)N=C(N5CCN(C(C)C)CCC5)N=C2C=C1OCCCN6CCCCC6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMF : 150 mg/mL (ultrasonic)|DMSO : 16.67 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)
Target
– Histone Methyltransferase
Isoform
– EHMT2/G9a/KMT1C
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
