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YB-0158
$850 – $7,600
Products Details
Product Description
– YB-0158 (Wnt pathway inhibitor 2) is a reverse-turn peptidomimetic and a potent colorectal cancer stem cell (CSC) targeting agent. YB-0158 disrupts Sam68-Src interactions and induces apoptosis in CRC cells. Anti-cancer activities[1].
Web ID
– HY-136541
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C32H32N7Na2O7P
References
– [1]Masibag AN, Bergin CJ, Haebe JR, et al. Pharmacological targeting of Sam68 functions in colorectal cancer stem cells. iScience. 2021;24(12):103442.
CAS Number
– 1144043-83-3
Molecular Weight
– 703.59
Compound Purity
– 99.80
SMILES
– O=P(O[Na])(O[Na])OC1=CC=C(C[C@H]2C(N(CC3=CC=CC4=C3NN=C4)C[C@H](N(C(NCC5=CC=CC=C5)=O)N(CC=C)C6)N2C6=O)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic;adjust pH to 1 with 1M HCl)
Target
– Apoptosis;Wnt
Pathway
– Apoptosis;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
