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OSMI-2

$410

Only 1000 item(s) left in stock.

Products Details

Product Description

– OSMI-2 (Compound 1b) is a cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-2 increases detained intron splicing in cells[1].

Web ID

– HY-135784

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C26H25N3O7S2

References

– [1]Martin SES, et al. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545.

CAS Number

– 2260542-60-5

Molecular Weight

– 555.62

SMILES

– O=C(OC)CN(C([C@@H](C1=CC=CC=C1OC)NS(=O)(C2=CC3=C(NC(C=C3)=O)C=C2)=O)=O)CC4=CC=CS4

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Acyltransferase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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