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hDHODH-IN-5
$131
Only 1000 item(s) left in stock.
Products Details
Product Description
– DHODH-IN-7 is a human dihydroorotate dehydrogenase (DHODH) inhibitor, with an IC50 of 0.91 μM. DHODH-IN-7 induces differentiation in acute myeloid leukemia[1].
Web ID
– HY-135664
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H21F3N2O2
References
– [1]Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016 Sep 28;7(12):1112-1117.
CAS Number
– 2029049-77-0
Molecular Weight
– 390.40
SMILES
– O=C(NCCC(N[C@@H]1CCCC2=C1C=CC=C2)=O)C3=CC=C(C(F)(F)F)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
