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AZ’6421
SKU
HY-135312-Get quote
Category Reference compound
Tags Cancer, Estrogen Receptor/ERR;PROTACs, PROTAC;Vitamin D Related/Nuclear Receptor
Products Details
Product Description
– AZ’6421 acts as Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor alpha. AZ’6421 has a potent anti-tumour effect to inhibit the uncontrolled cellular proliferation which arises from malignant disease. AZ’6421 can be used for the research of cancer such as breast cancer[1].
Web ID
– HY-135312
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C52H65F3N6O7S
References
– [1]Bin Yang, et al. Compounds and their use in treating cancer. Patent WO2019123367A1.
CAS Number
– 2361115-35-5
Molecular Weight
– 975.17
SMILES
– C[C@@H](N1CC(C)(F)C)CC2=C(NC3=C2C=CC=C3)[C@H]1C4=C(F)C=C(OCCCOCCCOCC(N[C@@H](C(C)(C)C)C(N5[C@H](C(NCC6=CC=C(C7=C(C)N=CS7)C=C6)=O)C[C@@H](O)C5)=O)=O)C=C4F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Estrogen Receptor/ERR;PROTACs
Pathway
– PROTAC;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.