Download Files:
Products Details
Product Description
– CPI-1328 is an EZH2 inhibitor with a Ki value of 63 fM.
Web ID
– HY-134899
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H36ClN3O4S
References
– [1]Stuckey JI, et al. Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity. J Biol Chem. 2021 Jan-Jun;296:100349.
CAS Number
– 2390367-27-6
Molecular Weight
– 546.12
SMILES
– ClC1=C2C(O[C@](O2)([C@]3([H])CC[C@H](CC3)N(C)C)C)=C(C4=C1CCN(C4=O)CC5=C(C=C(NC5=O)C)SC)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Isoform
– EZH2
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
