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Products Details
Product Description
– IQZ23 inhibits adipocyte differentiation via AMPK pathway activation. IQZ23 exerts a high efficacy in decreasing the triglyceride level (EC50=0.033 μM) in 3T3-L1 adipocytes. IQZ23 could be used for the research of obesity and related metabolic disorders[1].
Web ID
– HY-133556
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C26H29N5O2
References
– [1]Yong Rao, et al. Discovery of a Promising Agent IQZ23 for the Treatment of Obesity and Related Metabolic Disorders. Eur J Med Chem. 2020 Apr 15;192:112172.
CAS Number
– 2415643-79-5
Molecular Weight
– 443.54
SMILES
– COC1=CC=C(NC(C2=NC(C=CC=C3)=C3C(NCCCCN4CCCC4)=N2)=C5C=O)C5=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– AMPK
Isoform
– AMPK
Pathway
– Epigenetics;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
