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Products Details
Product Description
– Cavα2δ-IN-1 shows high selectivity for voltage-gated calcium channels Cavα2δ-1 (Ki 6 nM) versus Cavα2δ-2 (Ki ＞ 10000 nM).
Web ID
– HY-132932
Shipping
– Room temperature
Molecular Formula
– C18H27N5O
References
– [1]Fernández A, et al. Piperazinyl Bicyclic Derivatives as Selective Ligands of the α2δ-1 Subunit of Voltage-Gated Calcium Channels. ACS Med Chem Lett. 2021 Oct 5;12(11):1802-1809.
CAS Number
– 2416957-09-8
Molecular Weight
– 329.44
SMILES
– O=C1C(C=NC=C2)=C2N=C([C@H](N3C[C@@H](C)NCC3)CCC)N1CC
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Calcium Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
