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Products Details
Product Description
– AZ14145845 is a highly selective type I1/2 dual Mer/Axl kinase inhibitor with in vivo efficacy.
Web ID
– HY-132893
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H35N9O
References
– [1]McCoull W, et al. Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy. J Med Chem. 2021 Sep 23;64(18):13524-13539.
CAS Number
– 2830555-70-7
Molecular Weight
– 561.68
SMILES
– CC1=C(C2=CN=C(C3=NN=C(N(CC4=CN5C(C=C4)=NC=C5C6=CC=C(CN(C)C)C=C6)C)O3)C(C)=C2)C(C)=NN1C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– TAM Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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