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GX-201
$400 – $3,800
Products Details
Product Description
– GX-201 is a selective NaV1.7 inhibitor, with an IC50 of <3.2 nM for hNaV1.7[1].
Web ID
– HY-131870
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H27ClF4N2O4S
References
– [1]Girish Bankar, et al. Selective Na V 1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain. Cell Rep. 2018 Sep 18;24(12):3133-3145.
CAS Number
– 1788071-27-1
Molecular Weight
– 563.00
Compound Purity
– 99.14
SMILES
– O=C(C1=C(F)C=C(OCC2CCN(CC2)CC3=CC(C(F)(F)F)=CC=C3Cl)C(C4CC4)=C1)NS(=O)(C)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– Sodium Channel
Isoform
– Nav1.7
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
