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Products Details
Product Description
– Heliosupine N-oxide, Heliosupin metabolite, inhibits muscarinic acetylcholine receptor (mAChR) with the IC50 of 350 μM. Heliosupine N-oxide is a pyrrolizidine alkaloid (PA)[1].
Web ID
– HY-131574
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H31NO8
References
– [1]T. Schmeller, et al. Allelochemical Activities of Pyrrolizidine Alkaloids: Interactions with Neuroreceptors and Acetylcholine Related Enzymes.Journal of Chemical Ecology volume 23, pages399–416 (1997).
CAS Number
– 31701-88-9
Molecular Weight
– 413.46
SMILES
– [O-][N+]12[C@]([C@H](CC2)OC(/C(C)=CC)=O)([H])C(COC([C@@]([C@@H](O)C)(O)C(C)(O)C)=O)=CC1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Natural Products
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