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Products Details
Product Description
– SHP2-IN-5 (compound 1) is an inhibitor of SHP2 (IC50: 97 nM). SHP2 is a non-receptor protein tyrosine phosphatase associated with cell growth and proliferation. SHP2-IN-5 has the potential to inhibit cancer and SHP2-related human diseases[1].
Web ID
– HY-130631
Shipping
– Room temperature
Molecular Formula
– C12H8O6
References
– [1]Kim B, et al. Development and structure-activity relationship study of SHP2 inhibitor containing 3, 4, 6-trihydroxy-5-oxo-5H-benzo [7] annulene[J]. Bioorganic & Medicinal Chemistry Letters, 2020, 30(1): 126756.. . .
CAS Number
– 54755-93-0
Molecular Weight
– 248.19
SMILES
– OC1=CC=C(C=C(C(O)=O)C=C(O)C2=O)C2=C1O
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– SHP2
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
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