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(S,R,S)-AHPC-PEG5-COOH
$190 – $550
Products Details
Product Description
– (S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].
Web ID
– HY-130271
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C36H54N4O11S
References
– [1]Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.
CAS Number
– 2172820-14-1
Molecular Weight
– 750.90
Compound Purity
– 99.88
SMILES
– O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCOCCOCCOCCOCCC(O)=O)=O)=O)C[C@H](O)C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 200 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– von Hippel-Lindau (VHL)
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
