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SC-435
$350 – $8,200
Products Details
Product Description
– SC-435 is an apical sodium-dependent Bile acid (BA) transporter inhibitor. SC-435 can alter hepatic cholesterol metabolism and lower plasma low-density lipoprotein-cholesterol concentrations[1].
Web ID
– HY-129982
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C37H59N3O7S2
References
– [1]West KL, et, al. 1-[4-[4[(4R,5R)-3,3-Dibutyl-7-(dimethylamino)-2,3,4,5-tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl]phenoxy]butyl]-4-aza-1-azoniabicyclo[2.2.2]octane methanesulfonate (SC-435), an ileal apical sodium-codependent bile acid transporter inhibitor alters hepatic cholesterol metabolism and lowers plasma low-density lipoprotein-cholesterol concentrations in guinea pigs. J Pharmacol Exp Ther. 2002 Oct;303(1):293-9.
CAS Number
– 289037-67-8
Molecular Weight
– 722.01
Compound Purity
– 98.73
SMILES
– CS(=O)([O-])=O.O[C@@H]1[C@@](C2=CC=C(C=C2)OCCCC[N+]34CCN(CC4)CC3)([H])C5=CC(N(C)C)=CC=C5S(=O)(CC1(CCCC)CCCC)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : ≥ 50 mg/mL
Target
– Apical Sodium-Dependent Bile Acid Transporter
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
