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Products Details
Product Description
– 13-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis[1][2].
Web ID
– HY-129240S
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H23D3O3
References
– [1]A E Stuck, et al. Pharmacokinetics of acitretin and its 13-cis metabolite in patients on haemodialysis. Br J Clin Pharmacol. 1989 Mar; 27(3): 301–304.|[2]Berbis P, et al. Residual plasma concentrations of acitretin (Ro 10-1670) and its metabolite (Ro 13-7652) after chronic administration. Dermatologica. 1988;177(4):244-6.
CAS Number
– 1185241-03-5
Molecular Weight
– 329.45
SMILES
– O=C(/C=C(C=CC=C(C=CC1=C(C=C(C(C)=C1C)OC([2H])([2H])[2H])C)C)C)O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite;Isotope-Labeled Compounds
Pathway
– Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
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