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10β,17β-dihydroxyestra-1,4-dien-3-one
$80 – $960
Products Details
Product Description
– 10β,17β-dihydroxyestra-1,4-dien-3-one (DHED) is a brain-targeting bioprecursor proagent of the main human estrogen, 17β-estradiol, alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain[1].
Web ID
– HY-128976
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C18H24O3
References
– [1]Merchenthaler I, et al. Treatment with an orally bioavailable prodrug of 17β-estradiol alleviates hot flushes without hormonal effects in the periphery. Sci Rep. 2016 Aug 1;6:30721.
CAS Number
– 549-02-0
Molecular Weight
– 288.38
Compound Purity
– 98.89
SMILES
– C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(O)[C@@]3([H])CC2)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Estrogen Receptor/ERR
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
