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SIS17
$75 – $620
Products Details
Product Description
– SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM, inhibits the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs[1].
Web ID
– HY-128918
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C21H38N2OS
References
– [1]Son SI, et al. Activity-Guided Design of HDAC11-Specific Inhibitors. ACS Chem Biol. 2019 Jul 19;14(7):1393-1397.|[2]Li R, et al. A pan-cancer analysis identifies HDAC11 as an immunological and prognostic biomarker. FASEB J. 2022 Jul;36(7):e22326.
CAS Number
– 2374313-54-7
Molecular Weight
– 366.60
Compound Purity
– 99.65
SMILES
– O=C(C1=CC=CS1)NNCCCCCCCCCCCCCCCC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– HDAC
Isoform
– HDAC11
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
