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CBP/p300-IN-10
$450 – $12,800
Products Details
Product Description
– CBP/p300-IN-10 is a highly potent histone acetyltransferase EP300 and CREBBP with IC50 values of 26 nM and 39 nM, respectively. CBP/p300-IN-10 can be used to research anticancer[1].
Web ID
– HY-128875
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H24F5N5O3
References
– [1]Naito, Hiroyuki, et al. Preparation of amino acid amide derivatives such as L- and D-prolinamide derivatives as Ep300/CREBBP inhibitors. WO2018235966A1
CAS Number
– 2259641-71-7
Molecular Weight
– 537.48
Compound Purity
– 98.69
SMILES
– O=C(N1[C@H](C[C@H](C1)F)C(NC2=CC=C(NN=C3)C3=N2)=O)C4(C5=CC=C(C=C5)OC(F)F)CCC(F)(CC4)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10.5 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Histone Acetyltransferase
Isoform
– CBP/p300
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
