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Mal-VC-PAB-DM1

$320$4,000

Products Details

Product Description

– Mal-VC-PAB-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB [1].

Web ID

– HY-126682

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture and light)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C61H82ClN9O17

References

– [1]Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.

CAS Number

– 1464051-44-2

Molecular Weight

– 1248.81

Compound Purity

– 99.12

SMILES

– C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)C=C5)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 75 mg/mL (ultrasonic)

Target

– Drug-Linker Conjugates for ADC

Isoform

– Maytansinoids

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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