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Fluoflavine
$187 – $290
Products Details
Product Description
– Fluoflavine (ML-090) is a selective NOX1 inhibitor with an IC50 of 90 nM. Fluoflavine has >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50>10 μM). ML-090 has an IC50 of 360 nM in HEK293 cells[1].
Web ID
– HY-126195
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C14H10N4
References
– [1]SJ Brown, et al. Probe Report for NOX1 Inhibitors.
CAS Number
– 531-46-4
Molecular Weight
– 234.26
Compound Purity
– 99.41
SMILES
– C1(N2)=NC3=C(C=CC=C3)NC1=NC4=C2C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– NADPH Oxidase
Isoform
– NOX1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
