Download Files:
PARP11 inhibitor ITK7
$380 – $3,200
Products Details
Product Description
– PARP11 inhibitor ITK7 (ITK7) is a potent and selective PARP11 inhibitor. PARP11 inhibitor ITK7 can potently inhibit PARP11 with an IC50 value of 14 nM. PARP11 inhibitor ITK7 can be used for the research of cellular localization[1]. PARP11 inhibitor ITK7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-125218
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H14N4OS
References
– [1]Kirby, Ilsa T et al. A Potent and Selective PARP11 Inhibitor Suggests Coupling between Cellular Localization and Catalytic Activity. Cell chemical biology vol. 25,12 (2018): 1547-1553.e12.
CAS Number
– 2411890-36-1
Molecular Weight
– 322.38
Compound Purity
– 99.77
SMILES
– O=C1NC(CSC2=NC=CC=N2)=NC3=C1C=CC(C#CC)=C3C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– PARP
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
