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Naspm (trihydrochloride)
$106 – $891
Products Details
Product Description
– Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
Web ID
– HY-12506A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H37Cl3N4O
Citations
– Cell Rep. 2020 Nov 10;33(6):108369. |Cell Rep. 2023 Dec 3;42(12):113551.|iScience. 2023 Mar.|J Headache Pain. 2022 Aug 10;23(1):98.|Neuroscience. 2021 Sep 9;S0306-4522(21)00454-1.|Toxicol In Vitro. 2017 Oct;44:57-65.
References
– [1]Koike M, et al. Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci Res. 1997 Sep;29(1):27-36.
CAS Number
– 1049731-36-3
Molecular Weight
– 479.91
Compound Purity
– 99.47
SMILES
– [H]Cl.[H]Cl.[H]Cl.O=C(NCCCNCCCCNCCCN)CC1=C2C=CC=CC2=CC=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 6.4 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
Target
– iGluR
Isoform
– AMPA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
