Download Files:
Products Details
Product Description
– OHM1 is an analog of HIF1α CTAD that inhibits its binding with p300/CBP. OHM1 targets CH1 domain with an affinity of 0.53 μM[1].
Web ID
– HY-124722
Shipping
– Room temperature
Molecular Formula
– C24H42N6O5
References
– [1]Lao BB, et al. In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7531-6.
CAS Number
– 1450995-09-1
Molecular Weight
– 494.63
SMILES
– O=C(N)[C@@H](N1C([C@H](C)N(C([C@@H](N2C([C@H](CC(C)C)NCC2)=O)CC(C)C)=O)CC1)=O)CCC(N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
