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Cefatrizine
$211
Only 1000 item(s) left in stock.
Products Details
Product Description
– Cefatrizine (BL-S-640) is an orally active and broad-spectrum cephalosporin antibiotic. Cefatrizine is also a eEF2K inhibitor, with anti-proliferative activity in human breast cancer cells, which could induce ER stress, leading to cell death. Cefatrizine can be used in studies of cancer and bacterial infection[1][2].
Web ID
– HY-123024
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H18N6O5S2
References
– [1]Yao Z, et al. Integrative bioinformatics and proteomics-based discovery of an eEF2K inhibitor (cefatrizine) with ER stress modulation in breast cancer cells. Mol Biosyst. 2016 Mar;12(3):729-36. |[2]Leitner F, et al. BL-S640, a cephalosporin with a broad spectrum of antibacterial activity: bioavailability and therapeutic properties in rodents. Antimicrob Agents Chemother. 1975 Mar;7(3):306-10.
CAS Number
– 51627-14-6
Molecular Weight
– 462.50
SMILES
– O=C(O)C(N1[C@@]([H])([C@@H](C1=O)NC([C@@H](C2=CC=C(C=C2)O)N)=O)SC3)=C3CSC4=CNN=N4
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– H2O : 250 mg/mL (ultrasonic)
Target
– Antibiotic;Apoptosis;Bacterial
Isoform
– β-lactam
Pathway
– Anti-infection;Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
