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TIQ-A
$95 – $650
Products Details
Product Description
– TIQ-A is a potent TNKS (poly-ART, PARP) inhibitor, with an IC50 of 24 nM for TNKS2. TIQ-A is a potential anti-ischemic agent[1].
Web ID
– HY-121719
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C11H7NOS
References
– [1]Maksimainen MM, et al. Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs. Bioorg Med Chem. 2021 Dec 15;52:116511.
CAS Number
– 420849-22-5
Molecular Weight
– 201.24
Compound Purity
– 99.65
SMILES
– O=C1NC2=C(C3=C1C=CC=C3)C=CS2
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– PARP
Isoform
– PARP10;PARP14;PARP15;PARP2;TNKS2/PARP5B
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
