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Products Details
Product Description
– S 16474 is a cyclic peptide with antagonistic effects on NK1 and NK2 receptors. S 16474 can be used in the study of neurogenic inflammation[1].
Web ID
– HY-120928
Shipping
– Room temperature
Molecular Formula
– C44H47N6NaO8
References
– [1]Robineau P, et al. In vitro and in vivo pharmacology of S 16474, a novel dual tachykinin NK1 and NK2 receptor antagonist. Eur J Pharmacol. 1995 Dec 29;294(2-3):677-84.
CAS Number
– 149250-10-2
Molecular Weight
– 810.87
SMILES
– O=C([C@@H](N(CC1=CC=CC=C1)C)CC2=CC=CC=C2)NC([C@H](NC(C[C@@H]3NC([C@@]([H])(N4C3=O)C5CCC4CC5)=O)=O)CC6=CN(C7=C6C=CC=C7)C(CCC(O[Na])=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Neurokinin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
