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GSK-3β inhibitor 8
$103
Only 1000 item(s) left in stock.
Products Details
Product Description
– GSK-3β inhibitor 8, a thiophenacil derivative, is an effective and selective inhibitor of GSK-3β (IC50=64 nM). GSK-3β inhibitor 8 negatively regulated Wnt signaling pathway and stimulated β cell proliferation[1][2].
Web ID
– HY-120902
Shipping
– Room temperature
Molecular Formula
– C20H20ClN5OS
References
– [1]Wang W, et al. Identification of small-molecule inducers of pancreatic beta-cell expansion. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1427-32.
CAS Number
– 1139875-74-3
Molecular Weight
– 413.92
SMILES
– O=C(C1=CC=C(NC2=NC=CC(C3=CC=CS3)=N2)C=C1Cl)N4CCN(C)CC4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– GSK-3
Isoform
– GSK-3β
Pathway
– PI3K/Akt/mTOR;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
