Download Files:
CRT0273750
$71 – $1,600
Products Details
Product Description
– CRT0273750 is an autotaxin (ATX) inhibitor and modulates LPA levels in plasm (IC50 = 0.014 μM). CRT0273750 can be used in ATX/LPA-dependent models of cancer[1].
Web ID
– HY-120797
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H22ClF3N4O2
References
– [1]Shah P, et al. Discovery of potent inhibitors of the lysophospholipase autotaxin. Bioorg Med Chem Lett. 2016;26(22):5403-5410.
CAS Number
– 1979939-16-6
Molecular Weight
– 502.92
Compound Purity
– 98.72
SMILES
– FC(F)(OC1=CC=C(C=C1)CN2C(CCC(N[C@H](C3=CC=C(Cl)C=C3)C)=O)=NC4=CC=CN=C42)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– LPL Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
