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Nullscript
$158
Only 1000 item(s) left in stock.
Products Details
Product Description
– Nullscript is a negative control for Scriptaid. Nullscript is a known inactive analog of Scriptaid[1]. Scriptaid is a representative HDAC inhibitor[2]. Nullscript inhibits Cryptosporidium (C. parvum) growth with the IC50 value of 2.1 μM[3].
Web ID
– HY-118421
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C16H14N2O4
References
– [1]Fumi Murakoshi, et al. Nullscript inhibits <i>Cryptosporidium</i> and <i>Toxoplasma</i> growth. Int J Parasitol Drugs Drug Resist. 2020 Dec;14:159-166.|[2]Judith Clancy Keen, et al. A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2′-deoxycytidine. Breast Cancer Res Treat. 2003 |[3]Min Tong, et al. Histone deacetylase inhibitors and transforming growth factor-beta induce 15-hydroxyprostaglandin dehydrogenase expression in human lung adenocarcinoma cells. Biochem Pharmacol. 2006 Sep 14;72(6):701-9.
CAS Number
– 300816-11-9
Molecular Weight
– 298.29
SMILES
– O=C(N(C1=O)CCCC(NO)=O)C2=CC=CC3=CC=CC1=C23
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HDAC;Parasite
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
