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TAK-615
$110 – $1,780
Products Details
Product Description
– TAK-615 is a negative allosteric modulator (NAM) of the LPA1 receptor for the research of pulmonary fibrosis. TAK-615 binds the LPA1 receptor with high affinity (Kd high affinity of 1.7 nM and Kd low affinity of 14.5 nM)[1].
Web ID
– HY-117959
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H22FNO4
References
– [1]Jonathan Ellery, et al. Identification of Compounds Acting as Negative Allosteric Modulators of the LPA 1 Receptor. Eur J Pharmacol. 2018 Aug 15;833:8-15.
CAS Number
– 1664335-55-0
Molecular Weight
– 419.44
Compound Purity
– 98.97
SMILES
– O=C(O)C1=CC=C(CN(CC2CC2)C(C3=CC=C(OC4=CC=CC=C4F)C=C3)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– LPL Receptor
Isoform
– LPAR1
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
