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MHY908

Products Details

Product Description

– MHY908 is a potent dual agonist of PPARα and PPARγ[1]. MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity[2].

Web ID

– HY-117761

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C17H14ClNO3S

References

– [1]Park MH, et al. Potent anti-diabetic effects of MHY908, a newly synthesized PPAR α/γ dual agonist in db/db mice. PLoS One. 2013 Nov 14;8(11):e78815. |[2]Park MH, et al. Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2-methylpropanoic acid (MHY908). Arch Pharm Res. 2015 Apr;38(4):505-11.

CAS Number

– 1393371-39-5

Molecular Weight

– 347.82

SMILES

– CC(OC1=CC=C(C=C1)C2=NC3=CC(Cl)=CC=C3S2)(C(O)=O)C

Clinical Information

– No Development Reported

Research Area

– Cancer; Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– PPAR

Pathway

– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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