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Products Details
Product Description
– Carbonic anhydrase inhibitor 11 (compound VI) is a potent, selective carbonic anhydrase inhibitor. Carbonic anhydrase inhibitor 11 shows Ki values of 40, 39, 200 and 900 nM against CA II, IX, and XII, respectively[1].
Web ID
– HY-115998
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H15F3N4O3S2
References
– [1]Abdel-Mohsen HT, et al. Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine-Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors. Eur J Med Chem. 2022;228:114004.
CAS Number
– 2411059-71-5
Molecular Weight
– 468.47
SMILES
– O=S(C1=CC=C(NC2=NC(SCC(C3=CC=C(C(F)(F)F)C=C3)=O)=NC=C2)C=C1)(N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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