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AZD8154
$650 – $5,300
Products Details
Product Description
– AZD8154 is a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease.
Web ID
– HY-115870
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H29N5O4S2
References
– [1]Sadiq MW, et al. Characterisation of pharmacokinetics, safety and tolerability in a first-in-human study for AZD8154, a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease. Br J Clin Pharmacol. 2021 Jun 28.
CAS Number
– 2215022-45-8
Molecular Weight
– 551.68
Compound Purity
– 99.69
SMILES
– CS(=O)(C1=C2C(CN(C2=O)[C@H](C3CC3)C)=CC(C4=C(C)N=C(NC5=CC=CC(N6C(CCC6)=O)=N5)S4)=C1)=O
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– PI3K
Isoform
– PI3Kγ
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
