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Products Details
Product Description
– Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger[1][2][3].
Web ID
– HY-114457
Shipping
– Room temperature
Molecular Formula
– C47H85O19P3
References
– [1]Katan M, et, al. Phosphatidylinositol(4,5)bisphosphate: diverse functions at the plasma membrane. Essays Biochem. 2020 Sep 23;64(3):513-531. |[2]Arreola J, et, al. Wasted TMEM16A channels are rescued by phosphatidylinositol 4,5-bisphosphate Cell Calcium. 2019 Dec;84:102103. |[3]Kato M, et, al. Arabidopsis PCaP2 modulates the phosphatidylinositol 4,5-bisphosphate signal on the plasma membrane and attenuates root hair elongation. Plant J. 2019 Aug;99(4):610-625.
CAS Number
– 245126-95-8
Molecular Weight
– 1047.09
SMILES
– O=P(O)(O)O[C@H]1[C@@H]([C@H]([C@@H](O)[C@@H](OP(OC[C@@H](COC(CCCCCCCCCCCCCCCCC)=O)OC(CCC/C=CC/C=CC/C=CC/C=CCCCCC)=O)(O)=O)[C@@H]1O)O)OP(O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
