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Products Details
Product Description
– ROCK-IN-32 is a ROCK inhibitor, with an IC50 value of 11 nM for ROCK2. ROCK-IN-32 can be used in research of cardiovascular disease, cancer and inflammation[1].
Web ID
– HY-113641
Shipping
– Room temperature
Molecular Formula
– C20H17Cl2N3O2
References
– [1]Bosanac T, et al. Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3746-9.
CAS Number
– 1013117-40-2
Molecular Weight
– 402.27
SMILES
– ClC1=CC=C(C=C1)[C@H]2CNC[C@@H]2C(NC3=CC4=C(C=C3Cl)C(NC=C4)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
