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Sulfosuccinimidyl oleate (sodium)
$80 – $614
Products Details
Product Description
– Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate sodium is a potent and irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds the CD36 receptor on the surface of microglia. Anti-inflammatory effect[1][2].
Web ID
– HY-112847A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H36NNaO7S
Citations
– J Exp Med. 2023 Mar 6;220(3):e20221316.|J Transl Med. 2023 Feb 6;21(1):89.|Research Square Preprint. 2023 Oct 11.|Research Square Print. December 29th, 2022.|BMC Cancer. 2023 Apr 21;23(1):367.|Cancer Lett. 2023 Nov 25, 216511.|Cell Immunol. 11 January 2022, 104475.|CNS Neurosci Ther. 2023 May 8.|Food Res Int. 2023 Nov, 173, 113328.|Food Sci Nutr. 2023 Nov 22.|Front Pharmacol. 2020 Dec 16;11:593832.|Int J Biol Macromol. 2023 Oct 12:127324.|Int J Mol Sci. 2023 Aug 31, 24(17), 13516.|SSRN. 2023 Aug 30.|Toxicol Sci. 2022 Dec 19;kfac133.|Toxins. 2021, 13(11), 802.
References
– [1]Dhungana H, et al. Sulfosuccinimidyl oleate sodium is neuroprotective and alleviates stroke-induced neuroinflammation. J Neuroinflammation. 2017 Dec 4;14(1):237.|[2]Drahota Z, et al. Succinimidyl oleate, established inhibitor of CD36/FAT translocase inhibits complex III of mitochondrial respiratory chain. Biochem Biophys Res Commun. 2010 Jan 15;391(3):1348-51.
CAS Number
– 1212012-37-7
Molecular Weight
– 481.58
Compound Purity
– 98.0
SMILES
– O=S(C(C1)C(N(OC(CCCCCCC/C=CCCCCCCCC)=O)C1=O)=O)(O[Na])=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– Mitophagy
Pathway
– Autophagy
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
